Can I run Photoshop on a MacBook Pro 15"?

I'm planning on getting a Macbook Pro. I'm put between the choice of 15' or 17' but im thinking the 15' for me. I would like to have photoshop on it, can i get it on the 15' ?
also if you could aswell awnser this, what are the differences between these 2 Macbooks? what are the disadvantages?*** (sry for misspelled words)
please help with my choice!